The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Mar. 26, 2012
Applicants:

Mir Imran, Los Altos Hills, CA (US);

Mir Hashim, Fremont, CA (US);

Glen Mclaughlin, San Carlos, CA (US);

Huma Arastu, San Jose, CA (US);

Rekha Vaidyanathan, San Jose, CA (US);

Joel Harris, Mountain View, CA (US);

Radhika Korupolu, San Jose, CA (US);

Andrew Mangogna, San Jose, CA (US);

Chang Ong, San Jose, CA (US);

Sanjay Patel, San Jose, CA (US);

LU Wang, San Jose, CA (US);

Timothy Williams, San Jose, CA (US);

Inventors:

Mir Imran, Los Altos Hills, CA (US);

Mir Hashim, Fremont, CA (US);

Glen McLaughlin, San Carlos, CA (US);

Huma Arastu, San Jose, CA (US);

Rekha Vaidyanathan, San Jose, CA (US);

Joel Harris, Mountain View, CA (US);

Radhika Korupolu, San Jose, CA (US);

Andrew Mangogna, San Jose, CA (US);

Chang Ong, San Jose, CA (US);

Sanjay Patel, San Jose, CA (US);

Lu Wang, San Jose, CA (US);

Timothy Williams, San Jose, CA (US);

Assignee:

InCube Labs, LLC, San Jose, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 1/30 (2006.01); A61K 9/00 (2006.01); A61N 1/04 (2006.01); A61K 31/4178 (2006.01); A61K 31/4468 (2006.01); A61K 31/454 (2006.01); A61K 31/5415 (2006.01); A61N 1/32 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0009 (2013.01); A61K 9/0014 (2013.01); A61K 31/4178 (2013.01); A61K 31/4468 (2013.01); A61K 31/454 (2013.01); A61K 31/5415 (2013.01); A61N 1/044 (2013.01); A61N 1/0436 (2013.01); A61N 1/0448 (2013.01); A61N 1/30 (2013.01); A61N 1/303 (2013.01); A61N 1/325 (2013.01);
Abstract

Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.


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