The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Oct. 31, 2012
Applicant:

Counsyl, Inc., South San Francisco, CA (US);

Inventors:

Hunter Richards, San Francisco, CA (US);

Eric Evans, San Bruno, CA (US);

Balaji Srinivasan, South San Francisco, CA (US);

Subramaniam Srinivasan, Plainview, NY (US);

Abhik Shah, San Francisco, CA (US);

A. Scott Patterson, San Francisco, CA (US);

Clement Chu, San Francisco, CA (US);

Assignee:

Counsyl, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C40B 30/00 (2006.01); G06F 19/22 (2011.01); G06F 19/18 (2011.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G06F 19/22 (2013.01); C12Q 1/6874 (2013.01); C40B 30/00 (2013.01); G06F 19/18 (2013.01);
Abstract

The invention provides methods, apparatuses, and compositions for high-throughput amplification sequencing of specific target sequences in one or more samples. In some aspects, barcode-tagged polynucleotides are sequenced simultaneously and sample sources are identified on the basis of barcode sequences. In some aspects, sequencing data are used to determine one or more genotypes at one or more loci comprising a causal genetic variant. In some aspects, systems and methods of detecting genetic variation are provided.


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