The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Feb. 16, 2012
Applicants:
Leslie R. Berry, Burlington, CA;
Vera Ignjatovic, Armadale, AU;
Paul T. Monagle, East Bentleigh, AU;
Anthony K. Chan, Ancaster, CA;
Inventors:
Leslie R. Berry, Burlington, CA;
Vera Ignjatovic, Armadale, AU;
Paul T. Monagle, East Bentleigh, AU;
Anthony K. Chan, Ancaster, CA;
Assignees:
McMaster University, Hamilton, Ontario, CA;
The University of Melbourne, Victoria, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); G01N 33/86 (2006.01); C07K 5/087 (2006.01);
U.S. Cl.
CPC ...
G01N 33/86 (2013.01); C07K 5/0812 (2013.01);
Abstract
The invention provides novel reagents and methodologies for detecting free versus bound enzyme. It is particularly useful to detect thrombin when it is not bound to A2M in the presence of thrombin bound to A2M by using a modified substrate that is sterically hindered from reacting with the bound thrombin.