The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Sep. 07, 2006
Applicants:

Bastien Chevreux, Rheinfelden, DE;

Nigel J. Mouncey, Binningen, CH;

Masako Shinjoh, Kanagawa, JP;

Inventors:

Bastien Chevreux, Rheinfelden, DE;

Nigel J. Mouncey, Binningen, CH;

Masako Shinjoh, Kanagawa, JP;

Assignee:

DSM IP ASSETS B.V., Te Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01); C12P 17/04 (2006.01); C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12P 17/04 (2013.01); C12N 9/0004 (2013.01);
Abstract

Microorganism selected fromor, wherein a gene encoding a polypeptide with the activity of a repressor of L-sorbosone dehydrogenase (SNDH) and L-sorbose dehydrogenase (SDH) is disrupted. The gene has a polynucleotide selected from polynucleotides encoding a polypeptide comprising the amino acid sequence of which is represented by SEQ ID NO:2, polynucleotide comprising the nucleotide sequence according to SEQ ID NO:1, polynucleotides the complementary strand of which hybridizes under stringent conditions to a polynucleotide as defined above and which encodes a polypeptide with the activity of a repressor of SNDH and SDH. The microorganism produces at least 10% more Vitamin C and/or 2-KGA from L-sorbose compared to a microorganism wherein the repressor is intact.


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