The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Sep. 19, 2008
Partha Hazra, Karnataka, IN;
Srikanth Gollarahosahalli Sathyanarayana, Karnataka, IN;
Suma Sreenivas, Karnataka, IN;
Manjunath Hadavanahalli Shivarudraiah, Karnataka, IN;
Kedarnath Nanjund Sastry, Karnataka, IN;
Harish Iyer, Karnataka, IN;
Partha Hazra, Karnataka, IN;
Srikanth Gollarahosahalli Sathyanarayana, Karnataka, IN;
Suma Sreenivas, Karnataka, IN;
Manjunath Hadavanahalli Shivarudraiah, Karnataka, IN;
Kedarnath Nanjund Sastry, Karnataka, IN;
Harish Iyer, Karnataka, IN;
Biocon Limited, , IN;
Abstract
The present invention relates to the preparation of insulin compounds including their analogs or derivatives thereof from their corresponding precursor forms by a one step enzymatic reaction involving the combinatorial and concurrent use of optimal quantities of trypsin and carboxypeptidase B that work synergistically directing the reaction in a controlled manner to avoid production of random undesired byproducts. Particularly, the enzymatic conversion reactions of the instant invention offer advantages of reduction in the number operational steps, higher yield and purity of the desired end products.