The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

May. 22, 2014
Applicants:

Scott & White Healthcare, Temple, TX (US);

The Texas A&m University System, College Station, TX (US);

Inventors:

Robert Rosa, Holland, TX (US);

Gavin W. Roddy, Temple, TX (US);

Darwin J. Prockop, Philadelphia, PA (US);

Assignees:

Scott & White Healthcare, Temple, TX (US);

The Texas A&M University System, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 38/16 (2006.01); C07K 14/575 (2006.01); A61K 38/22 (2006.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
C07K 14/575 (2013.01); A61K 35/28 (2013.01); A61K 38/1709 (2013.01); A61K 38/22 (2013.01);
Abstract

The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.


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