The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Jun. 16, 2010
Kang LI, Richardson, TX (US);
Ping Wei, San Diego, CA (US);
Qinghai Peng, Del Mar, CA (US);
John Andrew Lippincott, San Mateo, CA (US);
Donna Marie Stone, Brisbane, CA (US);
Zdenek Hostomsky, La Jolla, CA (US);
Kang Li, Richardson, TX (US);
Ping Wei, San Diego, CA (US);
Qinghai Peng, Del Mar, CA (US);
John Andrew Lippincott, San Mateo, CA (US);
Donna Marie Stone, Brisbane, CA (US);
Zdenek Hostomsky, La Jolla, CA (US);
Pfizer Inc., New York, NY (US);
Abstract
This invention is directed toward monoclonal antibodies that bind specifically to Notch1. In one embodiment, the antibodies binds to at least a first epitope and a second epitope, wherein the first epitope resides with the LinA domain of the Notch1 negative regulatory region (NRR), and the second epitope resides within the HD-C domain of the Notch1 NRR.