The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Apr. 16, 2010
Applicants:

Tatsuki Yokoseki, Kanagawa, JP;

Yasuhide Okamoto, Kanagawa, JP;

Makoto Umeda, Kanagawa, JP;

Toshiyuki Ito, Kanagawa, JP;

Yukiho Imai, Kanagawa, JP;

Shinobu Fujii, Kanagawa, JP;

Naofumi Takamatsu, Kanagawa, JP;

Inventors:

Tatsuki Yokoseki, Kanagawa, JP;

Yasuhide Okamoto, Kanagawa, JP;

Makoto Umeda, Kanagawa, JP;

Toshiyuki Ito, Kanagawa, JP;

Yukiho Imai, Kanagawa, JP;

Shinobu Fujii, Kanagawa, JP;

Naofumi Takamatsu, Kanagawa, JP;

Assignee:

Immunas Pharma, Inc., Kanagawa, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/18 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); G01N 33/6896 (2013.01); C07K 2317/33 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01);
Abstract

The present inventors successfully produced monoclonal antibodies that are specific to only soluble A beta oligomers, but do not recognize soluble A beta monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.


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