The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
May. 17, 2011
Sai Reddy, Berkeley, IL (US);
Xin GE, Riverside, CA (US);
Jason Lavinder, Round Rock, TX (US);
Daniel Boutz, Austin, TX (US);
Andrew D. Ellington, Austin, TX (US);
Edward M. Marcotte, Austin, TX (US);
George Georgiou, Austin, TX (US);
Sai Reddy, Berkeley, IL (US);
Xin Ge, Riverside, CA (US);
Jason Lavinder, Round Rock, TX (US);
Daniel Boutz, Austin, TX (US);
Andrew D. Ellington, Austin, TX (US);
Edward M. Marcotte, Austin, TX (US);
George Georgiou, Austin, TX (US);
The Board of Regents of The University of Texas System, Austin, TX (US);
Abstract
Methods and compositions for identification of candidate antigen-specific variable regions as well as generation of antibodies or antigen-binding fragments that could have desired antigen specificity are provided. For example, in certain aspects methods for determining amino acid sequences of serum antibody CDR and abundancy level are described. In some aspects, methods for determining nucleic acid sequences of antibody variable region sequences and frequency are provided. Furthermore, the invention provides methods for identification and generation of antibody or antigen-binding fragments that comprise highly-represented CDR.