The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Aug. 29, 2014
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Craig A. Coburn, San Rafael, CA (US);

John A. McCauley, Maple Glen, PA (US);

Steven W. Ludmerer, North Wales, PA (US);

Kun Liu, Boston, MA (US);

Joseph P. Vacca, Telford, PA (US);

Hao Wu, Shanghai, CN;

Bin Hu, Shanghai, CN;

Richard Soll, San Diego, CA (US);

Fei Sun, Shanghai, CN;

Xinghai Wang, Shanghai, CN;

Man Yan, Shanghai, CN;

Chengren Zhang, Shanghai, CN;

Mingwei Zheng, Shanghai, CN;

Bin Zhong, Shanghai, CN;

Jian Zhu, Shanghai, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); C07D 405/14 (2006.01); C07K 5/08 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 498/10 (2006.01); A61K 31/437 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); A61K 45/06 (2006.01); C07K 5/06 (2006.01);
U.S. Cl.
CPC ...
C07K 5/08 (2013.01); A61K 31/437 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 498/10 (2013.01); C07K 5/06 (2013.01);
Abstract

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.


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