The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Mar. 02, 2012
Applicants:
Wang Shen, San Mateo, CA (US);
Aimin Zhang, Castro Valley, CA (US);
Jack Maung, Daly City, CA (US);
Xiaoling Zheng, Fremont, CA (US);
Inventors:
Wang Shen, San Mateo, CA (US);
Aimin Zhang, Castro Valley, CA (US);
Jack Maung, Daly City, CA (US);
Xiaoling Zheng, Fremont, CA (US);
Assignee:
NewGen Therapeutics, Inc., Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/06 (2006.01); A61K 31/517 (2006.01);
U.S. Cl.
CPC ...
C07D 405/06 (2013.01); A61K 31/517 (2013.01);
Abstract
The invention provides alkyne substituted quinazoline compounds, such as compounds of the formula (I), which are irreversible ErbB kinase inhibitors. The compounds are useful in the treatment of diseases and disorders where ErbB kinase activity is implicated such as a hyperproliferative disorder (e.g., cancer).