The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Sep. 22, 2008
Applicants:
Mark R. Kelley, Zionsville, IN (US);
Richard F. Borch, Lafayette, IN (US);
Rodney L. Nyland, Ii, Baltimore, MD (US);
Inventors:
Mark R. Kelley, Zionsville, IN (US);
Richard F. Borch, Lafayette, IN (US);
Rodney L. Nyland, II, Baltimore, MD (US);
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/02 (2006.01); A61K 31/196 (2006.01); A61K 45/06 (2006.01); A61K 31/122 (2006.01); A61K 31/13 (2006.01); A61K 31/195 (2006.01); A61K 31/203 (2006.01); A61K 31/282 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/122 (2013.01); A61K 31/13 (2013.01); A61K 31/195 (2013.01); A61K 31/203 (2013.01); A61K 31/282 (2013.01); A61K 31/454 (2013.01);
Abstract
This application describes quinone derivatives which target the redox site of Ape1/Ref1. Also included in the invention are pharmaceutical formulations containing the derivatives and therapeutic uses of the derivatives.