The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Jan. 26, 2012
Applicants:
Paul M. Dunman, Pittsford, NY (US);
Patrick D. Olson, St. Louis, MO (US);
Wayne Childers, New Hope, PA (US);
Inventors:
Paul M. Dunman, Pittsford, NY (US);
Patrick D. Olson, St. Louis, MO (US);
Wayne Childers, New Hope, PA (US);
Assignees:
University of Rochester, Rochester, NY (US);
Board of Regents of the University of Nebraska, Lincoln, NE (US);
Temple University—Of the Commonwealth System of Higher Education, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/68 (2006.01); A61K 31/341 (2006.01); C07D 307/56 (2006.01); C07D 405/06 (2006.01); C07D 417/06 (2006.01); A61K 31/427 (2006.01); A61K 45/06 (2006.01); A61K 31/402 (2006.01); C07D 207/337 (2006.01);
U.S. Cl.
CPC ...
A61K 31/341 (2013.01); C07D 307/56 (2013.01); C07D 307/68 (2013.01); A61K 31/402 (2013.01); A61K 31/427 (2013.01); A61K 45/06 (2013.01); C07D 207/337 (2013.01); C07D 405/06 (2013.01); C07D 417/06 (2013.01);
Abstract
Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease.