The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Aug. 25, 2008
Applicants:

Jacob Hendrik Beijnen, Amsterdam, NL;

Johannes Henricus Matthias Schellens, Amsterdam, NL;

Johannes Jan Moes, Amsterdam, NL;

Bastiaan Nuijen, Amsterdam, NL;

Inventors:

Jacob Hendrik Beijnen, Amsterdam, NL;

Johannes Henricus Matthias Schellens, Amsterdam, NL;

Johannes Jan Moes, Amsterdam, NL;

Bastiaan Nuijen, Amsterdam, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 31/337 (2006.01); A61K 9/16 (2006.01); A61K 9/48 (2006.01); A61K 31/427 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/337 (2013.01); A61K 9/1617 (2013.01); A61K 9/1635 (2013.01); A61K 9/1694 (2013.01); A61K 9/4858 (2013.01); A61K 31/427 (2013.01); A61K 9/0095 (2013.01);
Abstract

Pharmaceutical compositions and methods for the treatment of neoplastic disease and comprising the combination of a taxane, such as docetaxel, with a CYP3A4 inhibitor, such as ritonavir. Methods of treatment of neoplastic disease incorporating the administration of a taxane and the administration of a CYP3A4 inhibitor, either simultaneously or separately, are also included. Further, kits for carrying out the methods are included. Solid pharmaceutical taxane compositions for oral administration comprising a substantially amorphous taxane, a carrier and a surfactant are also included.


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