The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Mar. 07, 2011
Applicants:

Nicole Zitzmann, Oxford, GB;

Terry D. Butters, Oxfordshire, GB;

Frances M. Platt, Oxfordshire, GB;

Gary S. Jacob, Creve Coeur, MO (US);

Donald H. Picker, Warren, NJ (US);

Sandra Carrouee, Lyons, FR;

George W. J. Fleet, Oxfordshire, GB;

Raymond A. Dwek, Oxfordshire, GB;

David Durantel, Arles, FR;

Anand Mehta, Langdale, PA (US);

Timothy M. Block, Doylestown, PA (US);

Inventors:

Nicole Zitzmann, Oxford, GB;

Terry D. Butters, Oxfordshire, GB;

Frances M. Platt, Oxfordshire, GB;

Gary S. Jacob, Creve Coeur, MO (US);

Donald H. Picker, Warren, NJ (US);

Sandra Carrouee, Lyons, FR;

George W. J. Fleet, Oxfordshire, GB;

Raymond A. Dwek, Oxfordshire, GB;

David Durantel, Arles, FR;

Anand Mehta, Langdale, PA (US);

Timothy M. Block, Doylestown, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/45 (2006.01); A61P 31/12 (2006.01); A61K 31/13 (2006.01); A61K 31/00 (2006.01); A61K 31/166 (2006.01); A61K 31/40 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
A61K 31/13 (2013.01); A61K 31/00 (2013.01); A61K 31/166 (2013.01); A61K 31/40 (2013.01); A61K 31/445 (2013.01);
Abstract

Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C-Calkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.


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