The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Jun. 28, 2007
Applicants:
Michal Eisenbach-schwartz, Rehovot, IL;
Oleg Butovsky, Beer Sheva, IL;
Inventors:
Michal Eisenbach-Schwartz, Rehovot, IL;
Oleg Butovsky, Beer Sheva, IL;
Assignee:
YEDA RESEARCH AND DEVELOPMENT CO., LTD., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/02 (2006.01); A61K 38/07 (2006.01); A61K 35/12 (2006.01); A61K 39/00 (2006.01); A61K 35/17 (2015.01); A61K 35/15 (2015.01); A61K 38/10 (2006.01); A61K 38/20 (2006.01); C07K 5/10 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C12N 5/0783 (2010.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0007 (2013.01); A61K 35/15 (2013.01); A61K 35/17 (2013.01); A61K 38/10 (2013.01); A61K 38/16 (2013.01); A61K 38/2026 (2013.01); C07K 5/10 (2013.01); A61K 35/12 (2013.01); A61K 38/02 (2013.01); A61K 38/07 (2013.01); C07K 7/00 (2013.01); C07K 14/5406 (2013.01); C12N 5/0636 (2013.01);
Abstract
The invention provides methods and compositions for treatment of age-related macular degeneration, which comprises causing T cells that produce IL-4 to accumulate in the eye by administration of an agent such as Copolymer-1, IL-4, cells activated with IL-4, IL-13 or up to 20 ng/ml IFN-g, or a pathogenic self-antigen associated with a T-cell-mediated specific autoimmune disease of the eye or a peptide derived therefrom, and any combination of such agents.