The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 28, 2015
Filed:
Oct. 09, 2008
Applicants:
David Charles Jackson, North Balwyn, AU;
Weiguang Zeng, Kensington, AU;
Brendon Yew Loong Chua, Heidelberg Heights, AU;
Inventors:
David Charles Jackson, North Balwyn, AU;
Weiguang Zeng, Kensington, AU;
Brendon Yew Loong Chua, Heidelberg Heights, AU;
Assignee:
The University of Melbourne, , AU;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 15/87 (2006.01); C07K 1/107 (2006.01);
U.S. Cl.
CPC ...
A61K 39/00 (2013.01); C07K 1/1075 (2013.01); C12N 15/87 (2013.01); A61K 2039/53 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/622 (2013.01); C12N 2810/855 (2013.01);
Abstract
The present invention relates to the targeted delivery of molecules to cells expressing toll-like receptors (TLRs). Aspects of the invention provide compounds comprising a positively charged group linked to a TLR ligand. These compounds are useful for in vitro and in vivo methods of transfection of TLR-expressing cells. Other aspects of the invention relate to the use of such compounds for repression of gene expression and DNA vaccination approaches.