The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2015

Filed:

Mar. 28, 2011
Applicants:

Thomas W. Leonard, Wilmington, NC (US);

David C. Coughlan, Kildare, IE;

Alan Cullen, Dublin, IE;

Inventors:

Thomas W. Leonard, Wilmington, NC (US);

David C. Coughlan, Kildare, IE;

Alan Cullen, Dublin, IE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/21 (2006.01); A61K 8/30 (2006.01); A61Q 11/00 (2006.01); A61K 9/107 (2006.01); A61K 9/00 (2006.01); A61K 31/715 (2006.01); A61K 31/727 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 9/009 (2013.01); A61K 31/715 (2013.01); A61K 31/727 (2013.01); A61K 47/12 (2013.01);
Abstract

The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of selective factor Xa inhibitor in an object after oral administration comprising orally administering a pharmaceutical composition as described above.


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