The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Mar. 06, 2013
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Robert H. Blick, Madison, WI (US);

Abhishek Bhat, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 23/00 (2006.01); G01R 27/08 (2006.01); G01N 33/487 (2006.01); G01R 31/317 (2006.01); G01R 19/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48728 (2013.01); G01R 23/00 (2013.01); G01R 31/31708 (2013.01); G01R 19/0061 (2013.01);
Abstract

An antenna is used for radio frequency measurements of cell wall impedance changes due to ion channels. The antenna provides enhanced direct readout of lipid bilayers and cells containing pores and ion channels. The antenna is placed around a nanopore, which may be fabricated from glass, quartz or other material, and is shaped to provide an enhanced sensitivity to electrical activity in the vicinity of the nanopore. As such, the antenna may be of a class of bi-cone- or other stub-antennas providing high gain and broad bandwidth, for example a planar variant of a 'bow-tie' antenna. Accordingly, improved sensitivity of at least an order of magnitude may be achieved over past systems.


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