The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2015
Filed:
Feb. 06, 2012
Applicant:
Seiichi Oyadomari, Tokushima, JP;
Inventor:
Seiichi Oyadomari, Tokushima, JP;
Assignee:
THE UNIVERSITY OF TOKUSHIMA, Tokushima-Shi, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C12Q 1/02 (2006.01); G01N 33/50 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C07K 14/472 (2013.01); C12Y 104/03002 (2013.01); G01N 33/5008 (2013.01); G01N 33/5076 (2013.01); C07K 2319/60 (2013.01); G01N 2333/4706 (2013.01); G01N 2500/10 (2013.01); G01N 2800/042 (2013.01);
Abstract
A system for evaluating activation of the pathway mediated by ATF6. More specifically, a method for screening an endoplasmic reticulum stressor, as well as a method for screening a substance for suppressing an endoplasmic reticulum stress induced by the activation of the pathway mediated by ATF6, and a method for screening an antidiabetic drug candidate. A method for real-time evaluation of activation of the pathway mediated by ATF6 in viable cells. The method uses a polynucleotide encoding a nonfluorescent peptide domain derived from a fluorescent protein and an ATF6 protein domain.