The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9085773 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 21, 2015

Filed:

May. 07, 2013
Applicant:

Vivonics, Inc., Waltham, MA (US);

Inventor:

Vladimir Leo Gilman, Westford, MA (US);

Assignee:

Vivonics, Inc., Waltham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); C12Q 1/68 (2006.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C12N 2310/16 (2013.01); C12N 2320/11 (2013.01); C12N 2320/13 (2013.01);
Abstract

The present invention generally relates to methods for identifying nucleic acid ligands of a target molecule. In certain embodiments, the invention provides methods for identifying a nucleic acid ligand of a target molecule from a candidate mixture of nucleic acids, including contacting at least one target molecule with a candidate mixture of nucleic acids, in which the nucleic acids have different affinities for the target molecule, and separating in a single step nucleic acids that bind the target molecule with greatest affinity from nucleic acids that bind the target molecule with a lesser affinity and nucleic acids that do not bind the target molecule, thereby identifying the nucleic acid ligand of the target molecule.


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