The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2015
Filed:
Jul. 12, 2012
Charles L. Sawyers, Los Angeles, CA (US);
Mercedes E. Gorre, Los Angeles, CA (US);
Neil Pravin Shah, Woodland Hills, CA (US);
John Nicoll, Los Angeles, CA (US);
Charles L. Sawyers, Los Angeles, CA (US);
Mercedes E. Gorre, Los Angeles, CA (US);
Neil Pravin Shah, Woodland Hills, CA (US);
John Nicoll, Los Angeles, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The invention described herein relates to novel genes and their encoded proteins, termed Mutants Associated with Resistance to STI-571 (e.g., T315I Bcr-Abl), and to diagnostic and therapeutic methods and compositions useful in the management of various cancers that express MARS. The invention further provides methods for identifying molecules that bind to and/or modulate the functional activity of MARS.