The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Apr. 27, 2011
Applicants:

Hiroki Kusano, Toyonaka, JP;

Kenji Yamawaki, Toyonaka, JP;

Inventors:

Hiroki Kusano, Toyonaka, JP;

Kenji Yamawaki, Toyonaka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/546 (2006.01); C07D 501/56 (2006.01); C07D 501/42 (2006.01); C07D 501/44 (2006.01); C07D 501/46 (2006.01); C07D 519/00 (2006.01); C07D 519/06 (2006.01); C07D 501/54 (2006.01);
U.S. Cl.
CPC ...
C07D 501/56 (2013.01); C07D 501/42 (2013.01); C07D 501/44 (2013.01); C07D 501/46 (2013.01); C07D 501/54 (2013.01); C07D 519/00 (2013.01); C07D 519/06 (2013.01);
Abstract

Provided is a cephem compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria, and a pharmaceutical composition comprising the same. The cephem compound has the formula (I): where W and U are as defined in the specification; Ris as defined in the specification; Rand Rare as defined in the specification, provided that Rand Rare not taken together to form an optionally substituted oxime group when Ris aminothiazole or aminothiadiazole optionally protected at the amino group; ring A is a benzene ring or a 6-membered aromatic heterocyclic group having 1-3 nitrogen atoms; Ris a hydrogen atom, —OCHor —NH—CH(═O); k is an integer from 0 to 2; Ris as defined in the specification; and D and E are as defined in accordance with a) or b) described in the specification.


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