logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9085566 B1

PDFFull Text
Date of Patent:
Jul. 21, 2015

Filed:

Aug. 29, 2013

Compositions and methods for the treatment of metabolic and related disorders

Applicants:

Motonari Uesugi, Osaka, JP;

Salih J. Wakil, Houston, TX (US);

Lutfi Abu-elheiga, Houston, TX (US);

Mizuki Watanabe, Kyoto, JP;

Inventors:

Motonari Uesugi, Osaka, JP;

Salih J. Wakil, Houston, TX (US);

Lutfi Abu-Elheiga, Houston, TX (US);

Mizuki Watanabe, Kyoto, JP;

Assignee:

Baylor College of Medicine, Houston, TX (US);

Attorney:

Benjamin Aaron Adler

Primary Examiner:

Yong Chu

Int. Cl.
CPC ...
A61K 31/427 (2006.01); A61K 31/4025 (2006.01); C07D 417/04 (2006.01); C07D 403/04 (2006.01); A61K 31/4439 (2006.01); C07D 277/24 (2006.01); A61K 31/426 (2006.01); C07D 213/16 (2006.01); A61K 31/4418 (2006.01); A61K 31/454 (2006.01); C07D 213/76 (2006.01); A61K 31/496 (2006.01); C07D 235/14 (2006.01); C07D 417/12 (2006.01); A61K 45/06 (2006.01); C07D 417/14 (2006.01); C07D 277/22 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 277/52 (2006.01);
U.S. Cl.
CPC ...
C07D 417/04 (2013.01); A61K 31/426 (2013.01); A61K 31/4418 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01); C07D 213/16 (2013.01); C07D 213/76 (2013.01); C07D 235/14 (2013.01); C07D 277/22 (2013.01); C07D 277/24 (2013.01); C07D 277/52 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to the compound for treatment and/or prevention of one or more metabolic disorders utilizes an A-B-C tripartite structure, wherein A, B, and C are identical or non-identical structures, for example, but not limited to, heterocyclic, phenyl or benzyl ring structures with or without substitutions and are described in detail herein. Also provided are methods for the treatment and/or prevention of one or more metabolic disorders, for example, obesity or diabetes, utilizing fatostatin A and/or a derivative and/or analog thereof and/or the A-B-C tripartite compounds.

Find Patent Forward Citations

Loading…