The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Jan. 02, 2012
Applicants:

Eva Altmann, Reinach, CH;

Ulrich Hommel, Müllheim, DE;

Edwige Liliane Jeanne Lorthiois, Niffer, FR;

Juergen Klaus Maibaum, Weil-Haltingen, DE;

Nils Ostermann, Binzen, DE;

Jean Quancard, Huningue, FR;

Stefan Andreas Randl, Frankfurt am Main, DE;

Oliver Simic, Basel, CH;

Anna Vulpetti, Basel, CH;

Véronique Stark-rogel, Hésingue, FR;

Inventors:

Eva Altmann, Reinach, CH;

Ulrich Hommel, Müllheim, DE;

Edwige Liliane Jeanne Lorthiois, Niffer, FR;

Juergen Klaus Maibaum, Weil-Haltingen, DE;

Nils Ostermann, Binzen, DE;

Jean Quancard, Huningue, FR;

Stefan Andreas Randl, Frankfurt am Main, DE;

Olivier Rogel, Hésingue, FR;

Oliver Simic, Basel, CH;

Anna Vulpetti, Basel, CH;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 31/437 (2006.01); A61K 31/404 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/404 (2013.01); A61K 31/437 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.


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