The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Jan. 15, 2013
Applicant:

Astellas Pharma Inc., Tokyo, JP;

Inventors:

Takahiro Matsuya, Tokyo, JP;

Yutaka Kondoh, Tokyo, JP;

Itsuro Shimada, Tokyo, JP;

Shigetoshi Kikuchi, Tokyo, JP;

Maiko Iida, Tokyo, JP;

Kenichi Onda, Tokyo, JP;

Hiroki Fukudome, Tokyo, JP;

Yukihiro Takemoto, Tokyo, JP;

Nobuaki Shindou, Tokyo, JP;

Hideki Sakagami, Tokyo, JP;

Hisao Hamaguchi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 241/24 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 471/10 (2006.01); C07D 491/113 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 241/28 (2006.01); C07D 451/06 (2006.01); C07D 487/08 (2006.01); C07D 487/10 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 241/24 (2013.01); C07D 241/28 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 451/06 (2013.01); C07D 471/10 (2013.01); C07D 487/08 (2013.01); C07D 487/10 (2013.01); C07D 491/113 (2013.01);
Abstract

Compounds of formula (I): in which the variables are defined herein, are useful for the treatment of cancer in patients which express the EGFR T790M mutation.


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