The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2015
Filed:
Mar. 15, 2013
Applicants:
Alexandre Vasilievich Ivachtchenko, Encinitas, CA (US);
Oleg Dmitrievich Mitkin, Moscow reg., RU;
Inventors:
Alexandre Vasilievich Ivachtchenko, Encinitas, CA (US);
Oleg Dmitrievich Mitkin, Moscow reg., RU;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 233/86 (2006.01); C07D 491/107 (2006.01); C07D 471/10 (2006.01);
U.S. Cl.
CPC ...
C07D 233/86 (2013.01); C07D 471/10 (2013.01); C07D 491/107 (2013.01);
Abstract
The present invention relates to novel cyclic N,N'-diarylurea—androgen receptor antagonist, anti-cancer agent, pharmaceutical composition, medicament, and method for treatment of breast cancer disease. Cyclic N,N′-diarylthioureas or N,N′-diarylureas of the general formula 1, their optical (R)- and (S)-isomers and pharmaceutically acceptable salts thereof exhibiting properties of androgen receptor antagonists have been proposed,