The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 21, 2015
Filed:
Jul. 25, 2011
Applicants:
Zdenko Casar, Ljubljana, SI;
Damjan Sterk, Ljubljana, SI;
Marko Jukic, Ljubljana, SI;
Inventors:
Assignee:
LEK PHARMACEUTICALS D.D., Ljubljana, SI;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/12 (2006.01); C07D 239/42 (2006.01); C07C 45/68 (2006.01); C07C 49/807 (2006.01); C07D 215/14 (2006.01); C07D 239/46 (2006.01); C07C 49/86 (2006.01); C07D 215/12 (2006.01);
U.S. Cl.
CPC ...
C07D 239/42 (2013.01); C07C 45/68 (2013.01); C07C 49/807 (2013.01); C07C 49/86 (2013.01); C07D 215/12 (2013.01); C07D 215/14 (2013.01); C07D 239/46 (2013.01);
Abstract
The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.