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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9085529 B1

PDFFull Text
Date of Patent:
Jul. 21, 2015

Filed:

Aug. 22, 2011

Process for the preparation of intermediates useful for the manufacture nep inhibitors

Applicants:

David Hook, Rheinfelden, CH;

Bernhard Riss, Huningue, FR;

Jianguang Zhou, Suzhou, CH;

Yunzhong LI, Juangsu, CN;

Erhard Bappert, Weil am Rhein, DE;

Inventors:

David Hook, Rheinfelden, CH;

Bernhard Riss, Huningue, FR;

Jianguang Zhou, Suzhou, CH;

Yunzhong Li, Juangsu, CN;

Erhard Bappert, Weil am Rhein, DE;

Assignee:

Novartis AG, Basel, CH;

Attorneys:

Matthew Mulkeen

David Kurlandsky

Primary Examiner:

Robert Havlin

Int. Cl.
CPC ...
C07C 227/22 (2006.01); C07D 207/24 (2006.01); C07C 227/20 (2006.01); C07C 229/34 (2006.01); C07C 269/06 (2006.01); C07C 271/22 (2006.01); C07D 207/267 (2006.01); C07D 207/27 (2006.01); C07D 207/33 (2006.01); C07D 207/38 (2006.01); C07C 227/18 (2006.01); C07D 207/277 (2006.01);
U.S. Cl.
CPC ...
C07D 207/24 (2013.01); C07C 227/18 (2013.01); C07C 227/20 (2013.01); C07C 227/22 (2013.01); C07C 229/34 (2013.01); C07C 269/06 (2013.01); C07C 271/22 (2013.01); C07D 207/267 (2013.01); C07D 207/27 (2013.01); C07D 207/277 (2013.01); C07D 207/33 (2013.01); C07D 207/38 (2013.01); C07B 2200/07 (2013.01);
Abstract

The invention relates to a new process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a -amino- -biphenyl- -methylalkanoic acid, or acid ester, backbone, such as N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.

Find Patent Forward Citations

Quick Actions:

Hook, David. (2015). Process for the preparation of intermediates useful for the manufacture nep inhibitors (U.S. Patent No. 9085529). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9085529

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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