The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Nov. 05, 2012
Applicant:

Natreon, Inc., New Brunswick, NJ (US);

Inventors:

Shibnath Ghosal, Kolkata, IN;

Muruganandam Veeraragavan, Kolkata, IN;

Sanyasi R. Kalidindi, East Brunswick, NJ (US);

Assignee:

Natreon, Inc., New Brunswick, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 36/81 (2006.01); A61K 36/185 (2006.01); A01N 57/16 (2006.01); A61K 31/40 (2006.01); A61K 31/585 (2006.01); C07J 19/00 (2006.01); A61K 36/38 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/585 (2013.01); A61K 36/38 (2013.01); A61K 47/4803 (2013.01); A61K 47/48061 (2013.01); C07J 19/00 (2013.01);
Abstract

A group of indolealkylamino-withasteroid conjugates, isolated and purified from, are described. A synthetic method of making an indolealkylamino-withasteroid compound is provided. In vitro acetyl cholinesterase inhibitory activity and methods for treatment of dementia and dementia-related disorders, such as Alzheimer's disease, and anxiety and depressive disorders in mammals are demonstrated with these novel compositions.


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