The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Aug. 16, 2012
Applicants:

Jonathan Michael Ghergurovich, Collegeville, PA (US);

Michael Lee Moore, Collegeville, PA (US);

Cynthia Ann Parrish, Collegeville, PA (US);

Lance Howard Ridgers, Collegeville, PA (US);

Hongyi LU, Collegeville, PA (US);

Inventors:

Jonathan Michael Ghergurovich, Collegeville, PA (US);

Michael Lee Moore, Collegeville, PA (US);

Cynthia Ann Parrish, Collegeville, PA (US);

Lance Howard Ridgers, Collegeville, PA (US);

Hongyi Lu, Collegeville, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/10 (2006.01); A61K 31/5386 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5386 (2013.01); A61K 45/06 (2013.01); C07D 498/10 (2013.01);
Abstract

This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer.


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