The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Mar. 17, 2010
Applicants:

Tong Pu, Zhejiang, CN;

Yi Fan, Zhejiang, CN;

Tian Chen, Zhejiang, CN;

Ming Lei, Zhejiang, CN;

Naixing Wang, Zhejiang, CN;

Zhen Yang, Zhejiang, CN;

Jianming Yang, Zhejiang, CN;

Inventors:

Tong Pu, Zhejiang, CN;

Yi Fan, Zhejiang, CN;

Tian Chen, Zhejiang, CN;

Ming Lei, Zhejiang, CN;

Naixing Wang, Zhejiang, CN;

Zhen Yang, Zhejiang, CN;

Jianming Yang, Zhejiang, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 473/18 (2006.01); A61K 31/522 (2006.01);
U.S. Cl.
CPC ...
A61K 31/522 (2013.01); C07D 473/18 (2013.01);
Abstract

Preparation of acyclovir 2/3 hydrate comprises mixing acyclovir with water at weight ratio of 1:5˜50, dissolving at 50˜100° C., filtering, cooling filtrate at 0˜30° C. to precipitate crystal, collecting the crystal by filtration, and drying the crystal at 0˜150° C. for 0.5˜24 hours to obtain acyclovir 2/3 hydrate. The preparation process is simple and suitable for industrial production. The prepared product has good and stable crystal form.


Find Patent Forward Citations

Loading…