The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2015

Filed:

Jun. 15, 2012
Applicants:

Servet Buyuktimkin, San Diego, CA (US);

Nadir Buyuktimkin, San Diego, CA (US);

Jagat Singh, Toronto, CA;

John M. Newsam, La Jolla, CA (US);

Dominic King-smith, San Diego, CA (US);

Edward Kisak, San Diego, CA (US);

Inventors:

Servet Buyuktimkin, San Diego, CA (US);

Nadir Buyuktimkin, San Diego, CA (US);

Jagat Singh, Toronto, CA;

John M. Newsam, La Jolla, CA (US);

Dominic King-Smith, San Diego, CA (US);

Edward Kisak, San Diego, CA (US);

Assignee:

NUVO RESEARCH INC., Mississauga, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 33/02 (2006.01); A01N 33/24 (2006.01); A61K 31/13 (2006.01); A61K 31/135 (2006.01); A61K 31/137 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2006.01); A61K 47/20 (2006.01); A61K 47/34 (2006.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 9/0017 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01); A61K 47/186 (2013.01); A61K 47/20 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01);
Abstract

The present invention provides topical compositions, methods of preparation, and methods of treatment for onychomychosis. In certain specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a zwitterionic surfactant or charged derivative thereof; a carboxylic acid, a lower alcohol, and water. The acid is selected from a short-chain hydroxy acid, a short-chain fatty acid, and a mixture thereof. In certain other specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a quarternary amino acid, a keratolytic agent; a lower alcohol; and water. In certain embodiments, the keratolytic agent is urea, ammonium thioglycolate, or a mixture thereof.


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