The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Feb. 13, 2013
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Veit Peter Grunert, Munich, DE;

Ursula Klause, Indianapolis, IN (US);

Pavel Kubalec, Feldafing, DE;

Matthias Rothfuss, Penzburg, DE;

Barbara Upmeier, Iffeldorf, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); C40B 30/04 (2013.01); G01N 2800/52 (2013.01);
Abstract

Methods and system for determination of an anti-<therapeutic monoclonal antibody> antibody (anti-<TmAB>AB) in vitro in a sample from a patient treated with a therapeutic monoclonal antibody (TmAB). Also, methods and systems for the determination of antigen specific antibodies of a particular immunoglobulin class and for the identification of a patient who is at risk of developing an adverse drug reaction (ADR) during treatment with a TmAB.


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