The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Oct. 23, 2007
Applicants:

Pamela Contag, San Jose, CA (US);

Bradley W. Rice, Danville, CA (US);

Inventors:

Pamela Contag, San Jose, CA (US);

Bradley W. Rice, Danville, CA (US);

Assignee:

Xenogen Corporation, Alameda, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); G01N 21/64 (2006.01); A61B 19/00 (2006.01); A61B 18/20 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); A61B 19/52 (2013.01); G01N 21/6456 (2013.01); A61B 18/20 (2013.01); A61B 19/5244 (2013.01); A61B 2017/00057 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/00904 (2013.01); A61B 2019/5231 (2013.01); A61B 2019/5255 (2013.01); G01N 2201/1293 (2013.01);
Abstract

Disclosed are apparatus and methods for quantifying fluorescent distribution within a surgery site of a patient in an operating room, wherein the surgery site has been exposed for a surgery procedure. Excitation light is provided at each of a plurality of positions at the surgery site in a method embodiment. The excitation light is significantly more intense than any other light sources that are present in the operating room. Fluorescent emission is detected from the surgery site in response to each of the excitation light positions so as to obtain a fluorescent emission image for each excitation light position. The fluorescent light distribution that is internal to a surface of the surgery site is quantified based on the obtained fluorescent emission images. In one aspect, the quantifying operation includes utilizing a structured light source to form a structured light grid over the surgery site surface to thereby obtain a three dimensional (3D) surface mesh of the surface of the surgery site based on the structured light grid.


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