The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Apr. 11, 2012
Applicants:

Robert Blazej, San Francisco, CA (US);

Nicholas Toriello, Woodside, CA (US);

Charles Emrich, San Francisco, CA (US);

Richard N. Cohen, Oakland, CA (US);

Nitzan Koppel, Sunnyvale, CA (US);

Inventors:

Robert Blazej, San Francisco, CA (US);

Nicholas Toriello, Woodside, CA (US);

Charles Emrich, San Francisco, CA (US);

Richard N. Cohen, Oakland, CA (US);

Nitzan Koppel, Sunnyvale, CA (US);

Assignee:

Novozymes, A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/14 (2006.01); C12P 7/10 (2006.01); C12N 9/42 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2437 (2013.01);
Abstract

This invention provides novel variant cellulolytic enzymes having improved activity and/or stability. In certain embodiments the variant cellulotyic enzymes comprise a glycoside hydrolase with or comprising a substitution at one or more positions corresponding to one or more of residues F64, A226, and/or E246 inCelA enzyme. In certain embodiments the glycoside hydrolase is a variant of a family 9 glycoside hydrolase. In certain embodiments the glycoside hydrolase is a variant of a theme B family 9 glycoside hydrolase.


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