The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Sep. 07, 2011
Applicants:

Haval Shirwan, Louisville, KY (US);

Kutlu G. Elpek, Louisville, KY (US);

Esma S. Yolcu, Louisville, KY (US);

Inventors:

Haval Shirwan, Louisville, KY (US);

Kutlu G. Elpek, Louisville, KY (US);

Esma S. Yolcu, Louisville, KY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/70 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01); A61K 47/48 (2006.01); C12N 5/00 (2006.01); A61K 39/12 (2006.01); C07K 14/705 (2006.01); B82Y 5/00 (2011.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70532 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 45/06 (2013.01); A61K 47/4833 (2013.01); A61K 47/48353 (2013.01); B82Y 5/00 (2013.01); C07K 14/70575 (2013.01); C12N 5/0012 (2013.01); A61K 38/00 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/585 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/625 (2013.01); C12N 2710/20034 (2013.01); C12N 2760/16134 (2013.01);
Abstract

The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response against the antigen or infectious agent. The invention also provides immune cells modified with a conjugate that are useful for generating or enhancing an immune response to an antigen or infectious agent. The invention also provides immunostimulatory moieties comprising an immune co-stimulatory polypeptide that are useful for stimulating an immune response. The invention also provides immunotherapy methods and methods of treating or preventing infections.


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