The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Dec. 21, 2011
Applicants:
Andrew V Schally, Miami Beach, FL (US);
Ren Zhi Cai, Miami, FL (US);
Marta Zarandi, Szeged, HU;
Inventors:
Assignees:
The University of Miami, Miami, FL (US);
The United States of America, represented by the Department of Veterans Affairs, Washington, DC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 38/24 (2006.01); A61K 38/27 (2006.01); C07K 1/00 (2006.01); C07K 14/61 (2006.01); C07K 14/60 (2006.01);
U.S. Cl.
CPC ...
C07K 14/61 (2013.01); C07K 14/60 (2013.01); A61K 38/00 (2013.01);
Abstract
There are provided a novel series of peptide analogs of hGH-RH(1-29)NHand hGH-RH(1-30)NHwhich show high activities in stimulating the release of pituitary GH in animals. They retain their physiological activity in solution for extended periods of time and resist enzymic degradation in the body. These novel and useful properties appear to be due to novel substitution patterns ant at the 1, 15, 27 and 29 positions on the peptide.