The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Feb. 10, 2012
Applicants:

Toshiya Matsubara, Nishinomiya, JP;

Osamu Nishimura, Kawanishi, JP;

Susumu Iwasa, Kyotanabe, JP;

Makoto Watanabe, Osaka, JP;

Inventors:

Toshiya Matsubara, Nishinomiya, JP;

Osamu Nishimura, Kawanishi, JP;

Susumu Iwasa, Kyotanabe, JP;

Makoto Watanabe, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07K 14/52 (2006.01); C07K 14/475 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/52 (2013.01); C07K 14/475 (2013.01); C12Q 1/6883 (2013.01); G01N 33/68 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); G01N 2800/042 (2013.01);
Abstract

An insulin resistance marker, a method of evaluating insulin resistance, a method of screening a substance that improves insulin resistance, and a pharmaceutical composition for improving insulin resistance are provided. The insulin resistance marker includes a polypeptide comprising at least any 15 continuous amino acids in the specific amino acid sequence of SEQ ID NO: 1 (sequence of a proepithelin protein). The insulin resistance marker includes a polynucleotide selected from the group consisting of (1) a polynucleotide comprising at least any 45 continuous bases in the base sequence of SEQ ID NO:2 encoding the above specific amino acid sequence, and (2) a polynucleotide that is complementary to the polynucleotide of (1).


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