The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Jul. 21, 2010
Applicants:

John Mark Ellard, Hatfield, GB;

Christopher Neil Farthing, Hatfield, GB;

Adrian Hall, Hatfield, GB;

Inventors:

John Mark Ellard, Hatfield, GB;

Christopher Neil Farthing, Hatfield, GB;

Adrian Hall, Hatfield, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 31/5365 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01);
Abstract

A compound represented by the general formula: or a pharmaceutically acceptable salt thereof or a solvate thereof, wherein Ring A is a Caryl group or the like, L is —NRCO— or the like (wherein Ris a hydrogen atom or the like), Ring B is a Caryl group or the like, X is a Calkylene group or the like, Y is a single bond or the like, Z is a Calkylene group or the like, Rand Rare each independently a hydrogen atom or the like, and R, R, Rand Rare independently a hydrogen atom, a halogen atom or the like, has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.


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