The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Aug. 16, 2012
Applicants:
Thomas Dineen, Somerville, MA (US);
Isaac E Marx, Cambride, MA (US);
Hanh Nho Nguyen, Arlington, MA (US);
Matthew Weiss, Boston, MA (US);
Inventors:
Thomas Dineen, Somerville, MA (US);
Isaac E Marx, Cambride, MA (US);
Hanh Nho Nguyen, Arlington, MA (US);
Matthew Weiss, Boston, MA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/04 (2006.01); C07D 471/04 (2006.01); C07D 403/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 403/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract
The present invention provides compounds of Formula I or II, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.