The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Dec. 12, 2008
Applicants:

Kazuhisa Sugimoto, Osaka, JP;

Hiromi Nishiura, Osaka, JP;

Yoko Yamaguchi, Kawasaki, JP;

Keiichi Hirata, Kawasaki, JP;

Yoshiki Kubota, Kawasaki, JP;

Inventors:

Kazuhisa Sugimoto, Osaka, JP;

Hiromi Nishiura, Osaka, JP;

Yoko Yamaguchi, Kawasaki, JP;

Keiichi Hirata, Kawasaki, JP;

Yoshiki Kubota, Kawasaki, JP;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/385 (2006.01); C07D 339/04 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/51 (2006.01); B82Y 5/00 (2011.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
C07D 339/04 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0095 (2013.01); A61K 9/2018 (2013.01); A61K 9/5115 (2013.01); B82Y 5/00 (2013.01); A61K 9/14 (2013.01);
Abstract

Provision of a stable α-lipoic acid. A method for producing α-lipoic acid nanoparticles, the method comprising the steps of: preparing an aqueous dispersion liquid containing α-lipoic acid and a nonionic surfactant; adding a divalent metal salt into the aqueous dispersion liquid, wherein the divalent metal salt is a divalent metal halide, a divalent metal acetate or a divalent metal gluconate; and adding an alkali metal carbonate or an alkali metal phosphate into the aqueous dispersion liquid which has been added with the divalent metal salt, thereby forming α-lipoic acid nanoparticles.


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