The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Jul. 31, 2009
Applicants:
David Jaro Vocadlo, Burnaby, CA;
Ernest John Mceachern, Burnaby, CA;
Inventors:
David Jaro Vocadlo, Burnaby, CA;
Ernest John McEachern, Burnaby, CA;
Assignee:
Simon Fraser University, Burnaby, BC, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/60 (2006.01); C07D 263/52 (2006.01); A61K 31/428 (2006.01); A61K 31/423 (2006.01);
U.S. Cl.
CPC ...
C07D 263/52 (2013.01); A61K 31/423 (2013.01); A61K 31/428 (2013.01); C07D 277/60 (2013.01);
Abstract
The invention provides compounds of Formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcN Ac.