The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Aug. 31, 2012
Applicants:

JO Alen, Diepenbeek, BE;

Sandro Boland, Diepenbeek, BE;

Arnaud Pierre Jean Bourin, Diepenbeek, BE;

Olivier Defert, Diepenbeek, BE;

Dirk Leysen, Diepenbeek, BE;

Inventors:

Jo Alen, Diepenbeek, BE;

Sandro Boland, Diepenbeek, BE;

Arnaud Pierre Jean Bourin, Diepenbeek, BE;

Olivier Defert, Diepenbeek, BE;

Dirk Leysen, Diepenbeek, BE;

Assignee:

Amakem NV, Diepenbeek, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/00 (2006.01); C07D 213/79 (2006.01); C07D 213/74 (2006.01); A61K 31/44 (2006.01); A61K 31/443 (2006.01); C07D 213/75 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); C07D 401/12 (2006.01); C07D 417/12 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/74 (2013.01); A61K 31/44 (2013.01); A61K 31/443 (2013.01); C07D 213/75 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

The present invention relates to new kinase inhibitors, more specifically ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new ROCK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and respiratory diseases.


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