The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2015

Filed:

Nov. 08, 2011
Applicants:

Ian L. Scott, Monroe, WA (US);

Vladimir A. Kuksa, Seattle, WA (US);

Mark W. Orme, Seattle, WA (US);

Thomas Little, Redmond, WA (US);

Anna Gall, Woodinville, WA (US);

Feng Hong, Bellevue, WA (US);

Inventors:

Ian L. Scott, Monroe, WA (US);

Vladimir A. Kuksa, Seattle, WA (US);

Mark W. Orme, Seattle, WA (US);

Thomas Little, Redmond, WA (US);

Anna Gall, Woodinville, WA (US);

Feng Hong, Bellevue, WA (US);

Assignee:

ACUCELA INC., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09B 11/02 (2006.01); C07C 211/00 (2006.01); C07C 215/20 (2006.01); C07C 217/20 (2006.01); C07C 217/60 (2006.01); C07C 217/62 (2006.01); C07C 217/64 (2006.01); C07C 217/72 (2006.01); C07C 225/16 (2006.01); C07C 229/38 (2006.01); C07C 233/18 (2006.01); C07C 235/08 (2006.01); C07C 251/86 (2006.01); C07C 279/08 (2006.01); C07C 317/28 (2006.01); C07C 323/25 (2006.01); C07D 277/24 (2006.01); C07D 309/06 (2006.01);
U.S. Cl.
CPC ...
C07C 215/20 (2013.01); C07C 217/20 (2013.01); C07C 217/60 (2013.01); C07C 217/62 (2013.01); C07C 217/64 (2013.01); C07C 217/72 (2013.01); C07C 225/16 (2013.01); C07C 229/38 (2013.01); C07C 233/18 (2013.01); C07C 235/08 (2013.01); C07C 251/86 (2013.01); C07C 279/08 (2013.01); C07C 317/28 (2013.01); C07C 323/25 (2013.01); C07D 277/24 (2013.01); C07D 309/06 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2101/18 (2013.01); C07C 2102/42 (2013.01);
Abstract

The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.


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