The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Dec. 15, 2012
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Moungi G. Bawendi, Cambridge, MA (US);
He Wei, Cambridge, MA (US);
Numpon Insin, Sakon Nakhon, TH;
Hee-Sun Han, Cambridge, MA (US);
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 211/00 (2006.01); A61K 49/18 (2006.01); H01F 1/00 (2006.01); A61K 47/48 (2006.01); A61K 49/22 (2006.01); B22F 1/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1833 (2013.01); A61K 47/48861 (2013.01); A61K 49/186 (2013.01); A61K 49/1839 (2013.01); A61K 49/1866 (2013.01); A61K 49/222 (2013.01); B22F 1/0062 (2013.01); H01F 1/0054 (2013.01); B22F 1/0018 (2013.01); Y10T 428/2982 (2015.01);
Abstract
A water soluble nanoparticle can include a ligand of formula (I). The ligand can provide zwitterionic character and can provide water solubility, small hydrodynamic diameter, chemical stability, and the capability to modify the nanoparticle with additional functional moieties such as a small molecule, nucleic acid, or protein.