The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
May. 08, 2013
Applicant:
Northwestern University, Evanston, IL (US);
Inventor:
Rishi Arora, Chicago, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 49/00 (2006.01); A61K 38/18 (2006.01); A61B 5/042 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61B 5/0422 (2013.01); A61B 5/4839 (2013.01); A61K 38/1841 (2013.01); A61K 48/00 (2013.01); A61K 49/00 (2013.01); A61B 2562/046 (2013.01);
Abstract
The disclosed methods pertain to diagnosing whether a non-ablative, gene therapy is needed for reducing AF fibrosis in a subject, and if so, methods of reducing AF fibrosis in a subject using gene therapy with a dominant negative TGF-β R2 cDNA expression vector. Kits and computer program products are also described, wherein the kits provide materials for diagnosing and treating AF fibrosis, and the computer program products include a computer readable medium having computer readable program code for monitoring the efficacy of therapeutic ablation of fibrosis in a subject using a gene therapy method.