The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Jul. 01, 2011
Hyeong Kyu Lee, Daejeon, KR;
Kyung Seop Ahn, Daejeon, KR;
Yoosik Yoon, Seoul, KR;
Byoung Whui Choi, Seoul, KR;
Ok-kyoung Kwon, Daejeon, KR;
Semi Kim, Daejeon, KR;
Hui Seong Kim, Daejeon, KR;
Sei Ryang OH, Daejeon, KR;
Ji Eun Yuk, Daejeon, KR;
Ha Young Jang, Daejeon, KR;
Hyeong Kyu Lee, Daejeon, KR;
Kyung Seop Ahn, Daejeon, KR;
Yoosik Yoon, Seoul, KR;
Byoung Whui Choi, Seoul, KR;
Ok-Kyoung Kwon, Daejeon, KR;
Semi Kim, Daejeon, KR;
Hui Seong Kim, Daejeon, KR;
Sei Ryang Oh, Daejeon, KR;
Ji Eun Yuk, Daejeon, KR;
Ha Young Jang, Daejeon, KR;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a kit for the diagnosis or screening of asthma comprising neuropilin (NRP) gene, and to a method for screening a therapeutic agent for asthma using the same. More precisely, the present invention confirmed that NRP1 expression was increased in asthma patients and byextract. Based on the confirmation, the inventors confirmed that NRP1 could be effectively used as a target for the development of a therapeutic agent for asthma since the suppression of NRP1 expression resulted in the decrease of mRNA, protein, enzyme activity, and promoter activity of MMP-9 in relation to asthma.