The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Jun. 20, 2013
Applicant:
Normoxys, Inc., Brighton, MA (US);
Inventors:
Yves Claude Nicolau, Newton, MA (US);
Jean-Marie Lehn, Strasbourg, FR;
Konstantina C. Fylaktakidou, Thessaloniki, GR;
Ruth Greferath, Kehl, DE;
Assignee:
NormOxys, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/66 (2006.01); A61K 31/70 (2006.01); A61K 35/18 (2015.01); C07F 9/117 (2006.01); A61K 31/6615 (2006.01); A61K 31/715 (2006.01); C07F 9/6574 (2006.01); C07H 15/207 (2006.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
A61K 31/6615 (2013.01); A61K 31/66 (2013.01); A61K 31/70 (2013.01); A61K 31/715 (2013.01); A61K 35/18 (2013.01); C07F 9/117 (2013.01); C07F 9/65746 (2013.01); C07H 15/207 (2013.01); C12N 5/0641 (2013.01);
Abstract
The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphospahte (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention relates to compounds, compositions thereof, and methods that enhance the ability of mammalian red blood cells to deliver oxygen, by delivering IHP to the cytoplasm of the red blood cells.