The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2015
Filed:
Jun. 23, 2014
Applicant:
Trophogen Inc., Rockville, MD (US);
Inventors:
Mariusz W. Szkudlinski, Rockville, MD (US);
Bruce D. Weintraub, Rockville, MD (US);
Assignee:
Trophogen, Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); C07K 14/475 (2006.01); C07K 14/52 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1866 (2013.01); A61K 45/06 (2013.01); C07K 14/475 (2013.01); C07K 14/52 (2013.01); A61K 38/00 (2013.01);
Abstract
Modified VEGF proteins that inhibit VEGF-mediated activation or proliferation of endothelial cells are disclosed. The analogs may be used to inhibit VEGF-mediated activation of endothelial cells in angiogenesis-associated diseases such as cancer, inflammatory diseases, eye diseases, and skin disorders.